| Children |
| | 1. Doctor John Gabriel GUIGNARD, b. 14 Nov 1801, South Carolina d. 4 Dec 1857, Columbia, Richland District, South Carolina (Age 56 years) |
| | 2. James Sanders GUIGNARD, Jr., b. 1 Oct 1803 |
| | 3. Arena Magdalen GUIGNARD, b. 18 Mar 1806 d. 2 Aug 1810, Columbia, Richland District, South Carolina (Age 4 years) |
| | 4. William Maynard GUIGNARD, b. 22 Dec 1808 d. 9 Aug 1810, Columbia, Richland District, South Carolina (Age 1 year) |
| | 5. Caroline Elizabeth GUIGNARD, b. 14 Apr 1811, Columbia, Richland County, South Carolina d. 1 Feb 1865, Columbia, Richland County, South Carolina (Age 53 years) |
| | 6. Sarah Slann GUIGNARD, b. 1 Apr 1813 |
| | 7. Frances Ann Margaret Horry GUIGNARD, b. 5 Jan 1815 |
| | 8. Mary Susan Poinsett GUIGNARD, b. 9 Dec 1816, Columbia, Richland District, South Carolina d. 12 Mar 1873, Richland County, South Carolina (Age 56 years) |
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