| Children |
| | 1. Arthur MIDDLETON, b. 28 Oct 1795, Clifton, Gloucester d. 7 Jun 1853, Naples (Age 57 years) |
| | 2. Henry MIDDLETON, b. 16 Mar 1797, Parish Church of St. Andrew d. 15 Mar 1876, Washington, D.C. (Age 78 years) |
| | 3. Oliver Hering MIDDLETON, b. 12 Aug 1798, Clifton, Gloucester d. 17 Jan 1892, at the residence of General Rutledge, 44 South Bay, Charleston, South Carolina (Age 93 years) |
| | 4. John Izard MIDDLETON |
| | 5. a son MIDDLETON, b. 1801 d. an infant |
| | 6. William MIDDLETON |
| | 7. Maria Henrietta MIDDLETON, b. 14 Nov 1802, Cedar Grove d. 14 Jun 1838, at sea on the Pulaski (Age 35 years) |
| | 8. Eleanor MIDDLETON, b. 18 Jul 1804, Sullivan’s Island, South Carolina d. 1826, St Petersburg (Age 21 years) |
| | 9. Emma MIDDLETON, b. 16 Jun 1806, Charleston, South Carolina d. 3 Jul 1807 (Age 1 year) |
| | 10. Catherine MIDDLETON, b. 10 Sep 1812, Sullivan’s Island, South Carolina d. 1894 (Age 81 years) |
| | 11. Elizabeth Izard MIDDLETON, b. 9 Jun 1815, Charleston, South Carolina d. 19 Feb 1890, Philadelphia (Age 74 years) |
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